Pump & Pressure
- Dual high-pressure pump configuration for continuous pilot operation.
- Homogenization pressure up to ~30,000 psi (configuration dependent).
- Stable flow with minimized pressure pulsation.
Pilot Nano-Homogenizer
Genizer PilotGenizer Pilot Dual Pump Homogenizer
PilotGenizer Pilot Dual Pump — dual high-pressure pumps, up to ~30,000 psi (~2,000 bar), CIP/SIP compatible
Genizer PilotGenizer Pilot Dual Pump Homogenizer from Genizer is a pilot-scale high-pressure nano-homogenizer for continuous processing and scale-up of nano-scale pharmaceutical and biotech formulations.
Manufactured by
Genizer
Genizer PilotGenizer Pilot Dual Pump Homogenizer
Review the confirmed product information, including description, features, benefits, and applications.
The PilotGenizer Pilot Dual Pump is a pilot-scale high-pressure nano-homogenization system for formulation development, process optimization and scale-up studies between laboratory and commercial production. Its dual high-pressure pump architecture gives continuous, stable flow with minimized pressure pulsation for reproducible processing conditions.
The system operates at pressures up to approximately 30,000 psi (~2,000 bar, configuration dependent), forcing formulations through precision interaction chambers where shear, cavitation, turbulence and impact reduce particle size to sub-micron and nano-scale ranges with a narrow, repeatable distribution. It handles a wide range of viscosities and solid contents and supports technology transfer to production-scale systems such as ProdGenizer.
Wetted parts are pharmaceutical-grade stainless steel, and the unit is designed for GMP-oriented operation, including compatibility with Clean-In-Place (CIP) and Sterilize-In-Place (SIP) concepts, validation activities and integration into sterile production environments.
Processing Capability
- Precision interaction chamber technology.
- Sub-micron and nano-scale particle size capability.
- Suitable for low to high viscosity formulations.
Construction & Hygiene
- Pharmaceutical-grade stainless steel wetted parts.
- CIP / SIP compatible design.
- Designed for process development and scale-up.
Reproducible Pilot Runs
Provides highly reproducible processing at pilot scale.
Production Simulation
Gives an accurate simulation of commercial production conditions.
Lower Scale-Up Risk
Reduces scale-up risk when moving from pilot to production.
Consistent Quality
Delivers consistent particle size and formulation quality.
Validation Support
Supports formulation optimization and process validation.
Shorter Timelines
Shortens development and scale-up timelines.
The PilotGenizer is used for pilot-scale pharmaceutical manufacturing and formulation development of nano-scale products.
Pilot-Scale Manufacturing
Pilot-scale pharmaceutical manufacturing and formulation development work.
Vaccines and LNPs
Processing of vaccines and lipid nanoparticle (LNP) formulations.
Liposomal Drugs and Emulsions
Liposomal drug production and nano-emulsion processing.
Injectable and Oncology Products
Injectable suspensions, oncology and biotech formulations.
GMP-Oriented Design
GMP-oriented design (final compliance dependent on configuration and customer URS).
CE Compliance
CE compliance (final compliance dependent on configuration and customer URS).
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